disease

In two weeks Australia will play host to a major UN conference focusing on global health and the Millennium Development Goals. More than 70 countries and over 300 organisations will be represented. There will be many compelling stories that matter to Australia and our region. More details and downloads below.

Also, in Canberra today the Australian Academy of Science Think Tank is tackling questions regarding Australia’s mineral deposits. Will we run out of minerals? How much more mineral wealth is still to be found? Do we have the technologies to find it and extract it safely? The media releases are online at www.scienceinpublic.com.au/blog

These issues are being discussed in Canberra at a forum on 19 and 20 August. The media are invited to day one and the speakers are available for interview. The findings will be published later in the year. Read the full article →

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In two weeks Australia will play host to a major UN conference focusing on global health and the Millennium Development Goals. More than 70 countries and over 300 organisations will be represented. There will be many compelling stories that matter to Australia and our region. I’m holding briefings for ABC staff at Ultimo today at 3.30 pm and at Southbank on Monday at 12.30 pm. I’m happy to do the same for other major media.

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A compound produced by a pregnant lizard may provide important information on the origins and treatment of cancer in humans, according to zoologist Bridget Murphy from the University of Sydney, who discovered the protein, which is pivotal to the development of the lizard placenta.

“Our egg-laying ancestors probably never got cancer, but things changed when we started having live young. Embryos need an extensive network of blood vessels to allow them to grow. So do tumours.  I found that the three-toed skink, which gives birth to live young, uses a particularly powerful protein to encourage the growth of blood vessels. The only other place where this protein has been found is in pre-cancerous cells grown in the laboratory,” she says.

The placenta of the three toed skink is highly vascular (photo: Bridget Murphy)

Future research on unlocking the secrets of how the protein works might well provide the basis of new therapies for cancer, and to promote wound healing or the regeneration of blood vessels in patients with heart disease. Bridget’s work is being presented for the first time in public through Fresh Science, a communication boot camp for early career scientists held at the Melbourne Museum. She was one of 16 winners from across Australia.

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This is my occasional bulletin for journalists with an interest in science stories.

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People with diabetes invited to participate in trial

Media release: Geelong, Friday 23 April 2010

Modern drugs can stabilise adult onset diabetes but with some serious side effects. A Geelong-based company, Verva Pharmaceuticals, has a new approach – a drug used for many years to treat eye disease. In animal testing, the drug restored sensitivity to insulin. But will it be effective and safe in people? Read the full article →

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Most vaccines need a ‘magic’ booster or adjuvant to boost our immune response to the vaccine. But the best adjuvants are too toxic for human use.

Now NZ scientists believe they have created a powerful and safe adjuvant and are trialling it as part of a new cancer vaccine. Read the full article →

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How many viruses are there in your blood? How many dangerous nano-particles in your car exhaust?

qViro is a revolutionary New Zealand invention that offers the potential to quickly and cheaply answer these questions. It’s a feature of Ausbiotech – the national biotechnology conference – being held in Melbourne today. Read the full article →

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Ian Frazer

Follow this link to Ian Frazer’s acceptance speech: http://www.uq.edu.au/news/?article=16238

A hero of women and science

Ian Frazer has created four vaccines to fight cervical cancer. Two of them-Gardasil and Cervarix-are now on the market. Both prevent infection with the virus responsible for most cervical cancers. The other two vaccines are in clinical trials and are designed to treat women who have already been infected.

And Ian isn’t finished-he’s already working on the next generation of cervical cancer vaccines. But his greatest challenge is to get the vaccines to where they can do most good, in developing countries where screening programs are not widely available and 200,000 women die every year from cervical cancer.

Only then will his battle against cervical cancer be complete.

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Carola Vinuesa

Carola VinuesaWhen quality control fails in our immune system

Nature paper, child, Nature paper, child, Nature paper… Carola Vinuesa has had a busy few years. Her research has revealed key steps in how our immune system produces high quality, long lasting antibodies to fight disease.

And she has discovered what happens when things go wrong: that a single letter change in the genetic code is enough to create poor quality antibodies and trigger autoimmune diseases like lupus, juvenile diabetes and certain cancers.

This 39-year-old researcher’s work at the John Curtin School of Medical Research at the Australian National University is opening up new targets for drug discovery to fight autoimmune disease.

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New vaccine rollout through the GAVI Alliance expected to help extinguish childhood killer

Canberra, Australia — Papua New Guinea will begin immunising children this month with a vaccine that promises to rid the nation of Haemophilus Influenzae type b, or Hib disease, one of the deadliest causes of meningitis and pneumonia.

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Jamie RossjohnJamie Rossjohn

Proteins are the molecular machines of all life. Their shape is the key to understanding how they function, or malfunction. We can use this knowledge to understand the natural world, and to guide the development of tests, vaccines and drugs to fight disease.

Jamie Rossjohn is one of Australia’s leaders in structural biology and X-ray crystallography, a burgeoning field of science built around understanding the shape and function of proteins and other biological molecules. Read the full article →

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