Four new leads identified for anti-cancer drugs

Oz Research of Note (in progress)

Four new anti-cancer drug leads have been identified in an Australian study published online this week. The researchers undertook a comprehensive study that combined existing knowledge of an enzyme with a specifically tailored computational chemistry approach to identify novel inhibitors.

The enzyme (indoleamine 2,3-dioxygenase) has generated excitement amongst researchers over the past decade due to its increasing recognition role as a drug target, particularly for cancer.

Jason Smith, Macquarie University

Bioorganic and Medicinal Chemistry