In 2017, almost one million children fell ill and over 200,000 children under 15 died of tuberculosis, according to the latest WHO Roadmap. The report also identifies a previously underreported challenge, TB in adolescents.
Better vaccines are needed for the global fight against tuberculosis (TB). The Global Fund reports an estimated nine million new cases globally per year of TB, which is second only to AIDS as the world’s most deadly infectious disease. Indonesia had more than 320,000 reported cases in 2014 according to the World Health Organization, while Australia’s reported cases were just over 1,000. But the rise of drug-resistant TB poses a threat to all countries.
Two proteins from the tuberculosis bacterium have shown promising results in investigations in mice for a new vaccine. Scientists from the Centenary Institute and the University of Sydney, with colleagues at Universitas Gadjah Mada (UGM) in Yogyakarta, have found that the injected proteins can prime the immune system to induce protection against TB in mice.
The team has established a laboratory and immunological techniques to test if the two proteins from the tuberculosis bacterium can be used as the basis for a vaccine. Credit: Centenary Institute
Hari TB Sedunia (25 Maret) mengingatkan kita mengenai ancaman TB yang terus meningkat
Vaksin-vaksin yang lebih baik dibutuhkan agar dapat melawan TB di tingkat global. Global Fund melaporkan sekitar 9 juta kasus TB baru muncul setiap tahunnya, menempati posisi kedua sebagai penyakit menular paling mematikan di dunia setelah AIDS. Menurut Badan Kesehatan Dunia (WHO), lebih dari 320.000 kasus TB dilaporkan di Indonesia pada 2014. Sementara, hanya lebih dari 1.000 kasus TB yang dilaporkan di Australia. Namun, munculnya penyakit TB yang bersifat resistan terhadap obat menimbulkan ancaman bagi seluruh dunia.
China’s Ningxia Hospital sees more TB cases a year than the whole of Australia.
A new project at the hospital, in collaboration with researchers from the Centenary Institute in Sydney, aims to identify a new way of diagnosing TB and monitoring response to treatment. The research is funded in part by the Australian Respiratory Council.
