Nature paper: Turning on our immune sentries

A team from Melbourne, Monash, UQ and the synchrotron (including core members of the ARC Imaging Centre team) have found what sends our MAITs into action to protect our gut from invaders.

The patented work is the starting point to understanding our first line of defence, and what happens when it goes wrong.  It will lead to new ways of diagnosing and treating inflammatory bowel disease, peptic ulcers and even TB.

Contact Niall on niall@scienceinpublic.com.au to get in touch with the team.

Turning on our immune sentries

Melbourne, Monash, UQ and the synchrotron find what sends our MAITs into action to protect our gut from invaders.

T-cell-activation-by-transitory-antigens_smallOur guts, lungs and mouths are lined with mysterious immune cells that make up to ten per cent of the T cells in our immune system. Last year Australian researchers showed that these cells act as sentinels against invading bacteria and fungi. Now they’ve identified the precise biochemical key that wakes up these sentries and sends them into action.