The first Metcalf prizes; who’s who of Australian stem cell science; peer-review in action

National Stem Cell Foundation of Australia June newsletter

Welcome to the Foundation’s bulletin on stem cell science, news and our work in supporting stem cell research in Australia.

Australia is home to some remarkable stem cell researchers. Two of them were recognised today by our inaugural Metcalf Prizes.

Kaylene Young believes she can persuade certain lazy stem cells to repair brain injury. Jose Polo is unveiling the details of how stem cells can be produced from adult cells through a process of identity theft and reprogramming.

We’ve been able to award these prizes thanks to the generous support of our donors. We’re calling for more donations now to ensure we can offer future prizes and conduct other initiatives supporting stem cell research and community education.

One such initiative is the Foundation’s new Snapshot of Australian Stem Cell Science: May 2014, illustrating the depth and diversity of local stem cell research. Read on to find out more about the snapshot. Read More about The first Metcalf prizes; who’s who of Australian stem cell science; peer-review in action

New national stem cell prizes for Tasmanian and Melbourne researchers

Jose Polo, Donald Metcalf and Kaylene Young. Credit: Mark Coulson/NSCFACould we wake up our brain’s stem cells to repair injury and disease – Kaylene Young, Hobart

How adult cells change identity as they’re turned into stem cells – Jose Polo, Melbourne

Kaylene’s full profile and photos

Jose’s full profile and photos

Scientists available at 10am for photo call and interviews in their labs

Dr Kaylene Young of the Menzies Research Institute Tasmania and Dr Jose Polo of Monash University have both received inaugural $50,000 Metcalf Prizes from the National Stem Cell Foundation of Australia in recognition of their leadership in stem cell research.

Kaylene Young believes she can persuade lazy stem cells in our brain to repair brain injuries and even treat diseases such as multiple sclerosis and Alzheimer’s.

Kaylene and her colleagues have found neural stem cells and related progenitor cells—which feed, protect and assist nerve cells—in the outer part of the brain most prone to damage, known as the cortex.

By understanding the behaviour and function of these cells, they one day hope to use them for treating nervous and brain disorders or damage. Read More about New national stem cell prizes for Tasmanian and Melbourne researchers

Closer to repairing the brain with its own stem cells

Kaylene Young. Credit: Mark Coulson/NSCFAHobart researcher Kaylene Young believes she can persuade lazy stem cells in our brain to repair brain injuries and even treat diseases such as multiple sclerosis and Alzheimer’s.

Dr Kaylene Young of the Menzies Research Institute Tasmania has received an inaugural $50,000 Metcalf Prize from the National Stem Cell Foundation of Australia in recognition of her leadership in stem cell research.

She and her colleagues have found neural stem cells and oligodendrocyte progenitor cells (OPCs)—which feed, protect and assist nerve cells—in the outer part of the brain most prone to damage, known as the cortex.

By understanding the behaviour and function of these cells, they one day hope to use them for treating nervous and brain disorders or damage.

“Our ultimate goal is to harness the regenerative capacity of these cells for the treatment of neurodegenerative diseases, mental health disorders, and traumatic brain injury,” says Kaylene.

To assist in her work, the National Stem Cell Foundation of Australia has awarded Dr Kaylene Young—National Health and Medical Research Council RD Wright Biomedical Research Fellow and Research Group Leader at the University of Tasmania—one of two inaugural Donald Metcalf prizes each worth $50,000. Read More about Closer to repairing the brain with its own stem cells

New stem cells via identity theft and reprogramming

Jose Polo and Donald Metcalf. Credit: Mark Coulson/NSCFAJose Polo is unravelling the details of how stem cells can be produced from adult cells through a mix of identity theft and reprogramming. It is work that needs to be done before such stem cells can be used safely in medicine.

In recognition of his leadership in stem cell research, Associate Professor Polo of Monash University has received an inaugural $50,000 Metcalf Prize from the National Stem Cell Foundation of Australia.

The award is named for Australia’s pioneering stem cell researcher, Professor Donald Metcalf, AC, of the Walter and Eliza Hall Institute, who is an internationally renowned expert on haematopoiesis or blood cell formation.

Jose’s work is unveiling the development of induced pluripotent stem (iPS) cells —stem cells generated from skin, liver, blood or any other body cells. It is an important step along a path which could lead to treating degenerative diseases and understanding some cancers.

“When talking about my work, I often use the analogy of a library, where the genes in the cells are the books,” says Jose. “Every cell is a library which contains the same set of books, but they differ in terms of which ones are open and which are closed—in blood vessel cells the books on blood vessels will be open, and in pancreatic cells the books on the pancreas. I want to find the mechanism that opens and closes those books.”

Jose has already made two major strides forward. Read More about New stem cells via identity theft and reprogramming

Making eye cells from skin cells to understand blindness

Launch and embargo 10.30 am, 18 February 2013
Centre for Eye Research Australia, Level 1, 32 Gisborne Street, East Melbourne

With patient advocate, researcher, and stem cells

Media contacts:
Niall Byrne: 0417 131 977, niall@scienceinpublic.com.au
Georgina Howden Chitty: 0419 391 057, georgina@scienceinpublic.com.au

For CERA:
Emily Woodhams: 0408 370 959, emily.woodhams@unimelb.edu.au

Read More about Making eye cells from skin cells to understand blindness