Macquarie University and UWA scientists will join forces with two Australian companies to search for new antibiotics in 500,000 species of Australian microbes.
Background information below.
The project will be supported by a $3 million CRC-P grant announced by Australia’s Assistant Minister for Science, Jobs and Innovation, Senator Zed Seselja.
“We have samples of over 500,000 Australian microbes,” says Dr Ernest Lacey, Managing Director of Sydney-based company, Microbial Screening Technologies (MST), and the leader of the project.
Microbe-covered plates. Image credit: Andrew Piggott
“We’ve collected them from the soil in backyards, in paddocks, and forests. We’ve collected them from insects, plants and animals. We’ve gone everywhere to find Australia’s unique microbiome.”
“Each microbe contains a unique cocktail of metabolites. When we find an interesting new molecule, we’ll be relying on Macquarie University researcher Dr Andrew Piggott and his team to help us to work out its structure and mode of action.”
“Then Dr Heng Chooi from UWA will use genomics to unravel how the microbes assemble these metabolites and then boost their productivity.”
“Advanced Veterinary Therapeutics (AVT) is led by Dr Stephen Page and will focus on animal health potential,” says Dr Lacey.
“The CRC-P Program helps businesses, industries and research organisations to work together on short-term projects to develop practical solutions to challenges in key industry sectors,” Assistant Minister Seselja said at the project launch.
The three-year project, “BioAustralis, towards the future”, will harness MST’s unique collection as a source of next-generation antibiotics capable of overcoming microbial resistance. [continue reading…]