Dr Anai Gonzalez-Cordero research aims to restore sight in people with inherited retinal diseases, by repairing or replacing damaged photoreceptor (light-sensing) cells in the eye.
She has already shown that she can grow cultures of healthy photoreceptor cells in a dish in the lab and then use the cells replace the defective cells and restore sight in laboratory models of hereditary blindness. And she has shown that gene therapy can repair diseased human retinal cells grown in the lab as ‘mini-organs’ (or ‘organoids’), providing them with normal light-sensing ability.
Her $55,000 Metcalf Prize will contribute to developing systems to progress both concepts towards clinical trials. She is based at Children’s Medical Research Institute (CMRI) in Western Sydney.
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